The Super Berberine™

What is

GlucoVantage® is the first commercially available brand of Dihydroberberine (DHB), a derivative of berberine, which is an alkaloid isolated from Berberis Aristata.

Berberine has been used in Chinese and Ayurvedic medicine for decades and shown to be effective on optimizing blood glucose, improving insulin sensitivity and body composition, yet despite its demonstrated efficacy, berberine is limited by poor bioavailability.

Recent evidence demonstrates that DHB displays 5-fold better intestinal absorption than berberine in animals.

The Benefits:

DHB is more effective than berberine, as the active form, up to 5X more active/effective per the data.

Improves insulin sensitivity effectively via AMPK activation

Supports a healthy blood glucose level and insulin level

Anti-aging support reducing glycation (Advanced Glycation End-products) correlated with aging

Supports improved body composition and nutrient partitioning

How It Works

GlucoVantage® enhances insulin sensitivity effectively as well as inhibits adipocyte (fat cell) growth. Supports a healthy blood glucose level and insulin level.

May have synergy with exogenous ketone or MCT administration (e.g. KetoVantage® or C8Vantage™).



Bioactive Form of Berberine is DHB (up to 5x more effective)

More Cost Effective Due to Efficacy

Less Potential GI Distress than
Standard Berberine

No Adulteration or Herbal Spiking (HPLC/HPTLC)

Non-GMO, Natural, Made from Berberis Aristata

More Insulin Sensitivity, Glucose Disposal

DHB is a metabolite of berberine in the human body and has higher bioavailability than berberine. It’s the active form of berberine, that the gut must convert for berberine to be effectively utilized. Further, the gut microbiota is initiating this conversion from berberine to the active metabolite, DHB, and may be the reason some experience gastrointestinal (GI) distress with standard berberine.

New research is being conducted with DHB having potential synergy when co-administered with Bifidobacterium species enhancing the probiotic (as opposed to dysbiotic) nature of the gut.

How to Use

1 – 3

Servings per day

Take prior to meals
May have synergy when co-administered with probiotics
May have greater effect prior to carbohydrate containing meals
Topical application may possibly yield the greatest effect

100 – 200 mg

Per serving

Ways to use GlucoVantage:





Come Straight to the Source.

Please contact us for more scientific and technical information


Other Products

BHB Salts

MCT C8 Powder

L-β-Aminoisobutyric Acid