GlucoVantage® is the first commercially available brand of DHB and is produced from berberine.
Berberine is a plant alkaloid exists in Berberis family. It has been used in Chinese and Ayurvedic (Indian) medicine since 3000 BC. Berberine has proven to be effective on optimizing blood glucose, improving insulin sensitivity and body composition.
Studies show that human supplementation with Berberine for 3 months significantly improves insulin sensitivity and reduces body weight.
DHB is more effective than berberine, as the active form, up to 6X more active/effective per the data.
Improves insulin sensitivity effectively via AMPK activation
Supports a healthy blood glucose level and insulin level
Anti-aging support reducing glycation (Advanced Glycation End-products) correlated with aging
Supports improved body composition and nutrient partitioning
How It Works
GlucoVantage® enhances insulin sensitivity effectively as well as inhibits adipocyte (fat cell) growth. Supports a healthy blood glucose level and insulin level.
May have synergy with exogenous ketone or MCT administration (e.g. KetoVantage® or C8Vantage™).
Bioactive Form of Berberine is DHB (up to 6x more effective)
More Cost Effective Due to Efficacy
Less Potential GI Distress than
No Adulteration or Herbal Spiking (HPLC/HPTLC)
Non-GMO, Natural, Made from Berberis Aristata
More Insulin Sensitivity, Glucose Disposal
DHB is a metabolite of berberine in the human body and has higher bioavailability than berberine. It’s the active form of berberine, that the gut must convert for berberine to be effectively utilized. Further, the gut microbiota is initiating this conversion from berberine to the active metabolite, DHB, and may be the reason some experience gastrointestinal (GI) distress with standard berberine.
New research is being conducted with DHB having potential synergy when co-administered with Bifidobacterium species enhancing the probiotic (as opposed to dysbiotic) nature of the gut.
How to Use
1 – 3
Servings per day
Take prior to meals
May have synergy when co-administered with probiotics
May have greater effect prior to carbohydrate containing meals
Topical application may possibly yield the greatest effect
100 – 200 mg
Ways to use GlucoVantage: