GlucoVantage® is the first commercially available brand of Dihydroberberine (DHB), which is an active metabolite of berberine.
Berberine has been shown to optimize blood sugar, improving insulin sensitivity and body composition. Dihydroberberine solves berberine’s limitations of low bioavailability and GI distress.
Versus berberine, DHB has shown to be up to 5x more bioavailable/absorbable, and 2x longer-lasting (8 hours vs. 4 hours)
Improves insulin sensitivity and carbohydrate tolerance, supporting healthy blood glucose levels
Supports body composition via AMPK, preferentially driving carbohydrates to muscle rather than fat
Anti-aging support by reducing glycation end-products correlated with biological aging
Ketogenic-friendly by increasing plasma BHB (ketones). Reduced GI distress compared to berberine due to DHB being the gut’s active metabolite.
How It Works
GlucoVantage® enhances insulin sensitivity effectively as well as inhibits adipocyte (fat cell) growth. Supports a healthy blood glucose level and insulin level.
May have synergy with exogenous ketone or MCT administration (e.g. KetoVantage® or C8Vantage™).
Highly bioavailable form of berberine (up to 5x more effective)
More cost-effective alternative to berberine
Less potential GI distress than berberine
No Adulteration or Herbal Spiking (HPLC/HPTLC)
Non-GMO and derived from natural berberine
More Insulin Sensitivity, Glucose Disposal
Dihydroberberine (DHB) is a metabolite of berberine. Interestingly, gut microbes reduce berberine into its tissue-read form of DHB, which is then converted back to berberine after absorption in intestinal tissues.
In other words, supplementation with DHB bypasses the rate-limiting step of microbial reduction. This is why DHB has significantly greater functional benefits compared to berberine. Supplementation with DHB mitigates potential GI distress that some experience with berberine, which is likely the result of poor absorption and/or microbial reduction.
How to Use
1 – 2
Servings per day
Timing: prior to meals
Topical application may have added benefits.
May have synergy when co-administered with probiotics, exogenous ketones, and/or MCTs (e.g. KetoVantage® & C8VantageTM).
100 – 200 mg
Ways to use GlucoVantage: